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Sr. Principal Scientist

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Date: Sep 20, 2021

Location: Woburn, MA, US, 01801

Company: Corning

Requisition Number: 45870


Corning is one of the world’s leading innovators in materials science. For more than 160 years, Corning has applied its unparalleled expertise in specialty glass, ceramics, and optical physics to develop products that have created new industries and transformed people’s lives.

Corning succeeds through sustained investment in R&D, a unique combination of material and process innovation, and close collaboration with customers to solve tough technology challenges.

As a leading developer, manufacturer, and global supplier of scientific laboratory products for 100 years, Corning’s Life Sciences segment collaborates with researchers seeking new approaches to increase efficiencies, reduce costs and compress timelines in the drug discovery process. Using unique expertise in the fields of materials science, surface science, optics, biochemistry and biology, the segment provides innovative solutions that improve productivity and enable breakthrough discoveries.


Scope of Position:

Reporting to the Contract Services Manager, the position is responsible primarily for directing cytochrome P450 inhibition and induction, transporter, reaction phenotyping studies on behalf of clients using native and recombinant drug metabolizing enzyme test systems. Responsibilities include study protocol development, data interpretation, written and oral communication with the clients and writing reports. Ability to develop, continuously improve and champion, processes and procedures within a GLP and nonGLP environment. Leads R&D projects to enable the rapid and successful development of new services in a competitive market environment. The position will also involve direct management for a group of junior and senior scientists.


Day to Day Responsibilities:

  • Independently or with minimal direction to conduct studies and develops and prepares protocols for experiments of high complexity.
  • Expected to independently propose and execute approved technical projects and prepare reports, summaries and quantitative analyses of assigned research and continuous improvement projects.
  • Stays on top of the basic requirements for compliance in own area of work and aligns with those requirements.
  • Promotes a safe work environment.
  • May provide recommendations on maintaining the safety of the work environment.
  • Participates in Environmental, Health & Safety programs.


Travel Requirements:

  • Minimal travel less than 10% including attending conferences and customer visits.
  • No international travel is required.


Hours of work/work schedule/flex-time:

  • Full time; 40hr/week.


Required Education:

  • Required Ph.D. in chemistry, toxicology, pharmaceutics, analytical chemistry or related science.


Required Years and Area of Experience:

  • Minimum 8+ years of industry science experience.
  • Minimum 1+ years of leadership or supervisory experience.


Required Skills:

  • Significant knowledge and technical experience in, enzymology, drug metabolism, transport and techniques involving in vitro drug metabolism and drug-drug interactions.
  • Significant knowledge and technical experience in cell based- and microsome-based assay development.
  • Managerial and/or leadership potential required.
  • Familiarity with operation of common and more complex laboratory instrumentation and applicable computer software.


Desired Experience / Skills:

  • Strong knowledge and experience in other techniques such as plasma and microsomal protein binding, metabolite ID, LC/MS and interpretation of quantitative LC/MS data will be a plus.


Soft Skills:

  • Exercise good judgment in protection and dissemination of Company confidential and proprietary information.
  • Demonstrated ability to develop and follow established policies and procedures.
  • Strong initiative and ability to work independently identifying, investigating and developing solutions to problems.
  • Strong sense of urgency and work ethic and ability to complete projects within a defined time period.
  • Effective written and oral communication and interpersonal skills and ability to work effectively in a team environment.
  • Ability to effectively develop and maintain client relationships in the context of serving as a Study Director.
  • Demonstrated ability to keep neat, accurate, and complete records.


This position does not support immigration sponsorship.


We prohibit discrimination on the basis of race, color, gender, age, religion, national origin, sexual orientation, gender identity or expression, disability, veteran status or any other legally protected status.


We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Nearest Major Market: Woburn
Nearest Secondary Market: Boston